Andy Roddick at full stretch during his defeat to Uruguay's Pablo Cuevas at the Sony Ericsson Open in Miami.
STORY HIGHLIGHTS
- Andy Roddick beaten in straight sets by Uruguay's Pablo Cuevas at Sony Ericsson Open
- Roger Federer progresses to next round and breaks another career record
- Svetlana Kuznetsova knocked out in third round, losing 6-3 6-1 to China's Peng Shuai
(CNN) -- Reigning champion Andy Roddick suffered a shock defeat in the second round of the Sony Ericsson Open in Miami on Saturday losing 6-4 7-6 (4) to Uruguay's Pablo Cuevas.
The eighth seed looked out of sorts serving six double faults during the match.
Conversely, 25-year-old Cuevas produced some of his best tennis, serving 15 aces which helped seal victory over a top 10 player for the first time in his career.
Roddick is the second high-profile casualty in the men's draw after Andy Murray exited the tournament on Friday -- the Scot tamely surrendering to Alex Bogomolov Jr 6-1 7-5.
Cuevas will now face France's Giles Simon who defeated qualifier Rainer Schuettler in straight sets 6-4 6-3.
Roger Federer enjoyed a comfortable 6-3 6-3 win over Radek Stepanek from the Czech Republic.
I've never missed big chunks of seasons. That's how you end up with so many wins, I guess
--Roger Federer
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The straight-sets victory gave the world number three yet another career record as he joined Pete Sampras in seventh place on the all-time wins list with 762 -- Jimmy Connors holds the record for most wins with 1,242.
"It's a funny stat, but it shows how long I have been around already, how much I've won, all around the world and all the different surfaces. I've played 10, 12 solid seasons, you know. I've never missed big chunks of seasons. That's how you end up with so many wins, I guess," Federer said afterwards, AFP reported.
Federer will now face Juan Monaco in the next round after the Argentine beat Sergiy Stakhovsky of the Ukraine 6-4 6-7 (2) 6-4.
In the other men's matches, Jo-Wilfried Tsonga booked his place in the third round by beating Russia's Teymuraz Gabashvili 6-3 6-7 (3) 6-3. The win sets up a meeting with Alexandr Dolgopolov, who beat Andreas Seppi 6-1 5-3 -- the Italian was forced to retire with a sprained ankle.
Russia's Mikhail Youzhny made light work of the challenge from Taiwan's Lu Yen-Hsun thrashing him 6-1 6-0.
Youzhny will now face the Belgian qualifier Olivier Rochus in the next round after he inflicted a surprise 6-2 4-6 6-4 defeat on number 22 seed Marcos Baghdatis.
Philipp Petzschner triumphed over his doubles partner and 10th seed Jurgen Melzer 6-3, 6-4 to set up a meeting with either Janko Tipsarevic or Marin Cilic.
Meanwhile, in the women's event, Svetlana Kuznetsova crashed out in the third round, going down 6-3 6-1 to Peng Shuai from China.
Wozniacki overcomes brief scare
Shuai took control early on breaking the world number 15 in her opening service game and never really looked back, defeating the Russian for the second time this season in just one hour and 16 minutes.
The victory earns Shuai a fourth round date with number 26 seed Alexandra Dulgheru who beat Sweden's Johanna Larrson 6-2 6-1.
Maria Sharapova also progressed to the fourth round with a comfortable 6-2 6-0 victory over Germany's Sabine Lisicki.
In the other women's matches, Serbia's Ana Ivanovic beat Japan's Kimiko Date Krumm 6-2 6-0, while Jelena Jankovic overcame Klara Zakopalova 7-5 6-1.
Anabel Medina Garrigues defeated Russia's Elena Vesnina 6-3 6-4 and Australia's Samantha Stosur also dispatched her third round opponent Lucie Safarova in straight sets 6-0 7-6.